Metroid

 Another great game series developed by Nintendo is Metroid. The series revolves around the main character Samus Aran, who is a bounty hunter from the Galactic Federation. Apparently she is tracking a group of Space Pirates and their leader Ridley, who seemed to have an operation on the Planet Zebes in  the FS-176 system. Ridley came into contact with an aurora unit built by the Chozo, that acts as a super computer maintaining the planet Zebes. Somehow her programming became corrupt and she wished to bring order to the Universe and found the pirates as a useful tool. There she used her resources to defend the Space Pirates and Ridley. Being a great Bounty Hunter, Samus located what had been assisting the Space Pirates and a confrontation with Mother Brain.

She reported back to the Galactic Federation, and brought with her a number of specimens from Zebes. Of most interest was the Chozo bioweapon designated as a Metroid. They were first sighted on SR388, but thanks to Samus it could be safely studied. It was discovered that these bioweapons could mutate and were influenced by their environment. What was most interesting they also evolved from a jellyfish like form to an insect, and then into a reptilian.

Another legacy of the Chozo, was the deadly Phazon radiation that was semi-sentient. Phazon, appeared to be a highly mutagenic compound that could devastate an entire ecosystem and spread as a mass. It could also replicate biological entities if given suitable DNA. It is considered high dangerous. On the Aether it caused  dimensional instability, opening a gateway into a parallel world.

The elder races of the galaxy are the Chozo (avians), Luminoth (insects), Bryyonian (reptillian),  and the Alimbic (insects). They left a legacy of advanced technology on many of the planets explored by Samus.
Within the Galactic federation there are also a multitude of races such as; Humans, Enoema, Kriken (insects), Vhozon, Phyrigisians, Diamont (rock), Ing, Ylla, N'kren, Jovian, and the unnamed USR races (elf, simian, horned humaoinds). A number of star systems are traveled through; FS-176 (Zebes, Twin Tabula, Oormine II, Bilium, Talon IV), Alimbic cluster (Alinos, Arcterra), Dasha (Aether), Federation System (Bryyo, Elysia, Norion), SR388, Messina (Charybdis, Interia, Scylla), and other planets (Bes II, Daiban, Jamoru, Jatsuk, Jigrad, K-2L, Naishii, Phaaze, RX338, Solarion 12, Vho, 2466 URSA) .